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Even though recent genetic studies identified over 50 genetic locations, dietary interventions and proper lifestyle changes can prevent obesity development in genetically predisposed people.

Therefore, screening programs could be useful in identifying high-risk children, who could benefit from proper prophylactic measures. Perhaps, further studies should also focus on developing targeted genetic interventions designed for children that carry the burden of obesity risk.

Nutrigenomics intervention directing macronutrient breakdown, encouraging substitution of healthy foods with appropriate caloric intake, encouraging physical activity and behavioral modifications could begin easily at home.

Obesity during childhood can have a harmful effect on the body in a variety of ways. Children who have obesity are more likely to have:

  • High blood pressure and high cholesterol, which are risk factors for cardiovascular disease (CVD).
  • Increased risk of impaired glucose tolerance, insulin resistance, and type 2 diabetes.
  • Breathing problems, such as asthma and sleep apnea.
  • Joint problems and musculoskeletal discomfort.
  • Fatty liver disease, gallstones, and gastro-esophageal reflux (i.e., heartburn).

Childhood obesity is also related to:

  • Psychological problems such as anxiety and depression.
  • Low self-esteem and lower self-reported quality of life.
  • Social problems such as bullying and stigma.

Childhood obesity begins at home and so do the above complications that arise from not addressing the problem early before it migrates into adulthood.